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起止时间:2021-02-25到2021-07-01
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Introduction of Molecular cell biology Cell theory-test
1、 What did Leeuwenhoek do?
A: Looked at cork
B:Stated that plants are made of cells
C: Stated that animals are made of cells
D:Used simple light microscope and saw microorganisms
答案: Used simple light microscope and saw microorganisms
2、 He discovered that all animals were made of cells, which contributed to the development of the cell theory:
A:A.van Leeuwenhoek
B: Robert Hooke
C: Zacharias Jansse
D:Theodor Schwann
答案: Theodor Schwann
3、 Who was the first person to see cells under the microscope and give them a name?
A:A.van Leeuwenhoek
B:Robert Hooke
C:Theodor Schwann
D:Zacharias Jansse
答案: Robert Hooke
4、 Which of the following is NOT one of the main components of the cell theory?
A:cells must contain DNA
B: all living things are made of cells
C:cells can only come from other cells
D:cells are the basic unit of life
答案: cells must contain DNA
Biomembrane Structure Biomembrane Structure-test
1、 All the following statements describe biomembranes except:

B: The two leaflets of a biomembrane may contain different phospholipids.
C: Some biomembranes have free edges.
D:Some phospholipids and cholesterol may cluster to form lipid rafts.
答案: Some biomembranes have free edges.
2、 The major site of lipid synthesis in eukaryotic cells is the
A:Nucleus
B:Endoplasmic reticulum
C:Mitochondria
D:Cell membrane
答案: Endoplasmic reticulum
3、 Phospholipids with short or unsaturated fatty acyl chains
A:decrease membrane fluidity.
B:increase membrane fluidity.
C: cause biomembranes to become thicker
D:allow hydrophilic molecules to diffuse across the lipid bilayer.
答案: increase membrane fluidity.
4、 The _ are transmembrane proteins.
A:lipid-anchored membrane proteins
B:integral membrane proteins
C:peripheral membrane proteins
D:extracellular matrix proteins
答案: integral membrane proteins
5、 Glycolipids and glycoproteins are especially abundant in the
A: nucleus.
B:mitochondrial inner membrane
C:cytosol
D:plasma membrane
答案: plasma membrane
6、 Phosphate containing lipids include all of the following except
A: phospholipids.
B:sphingolipid
C:triglyceride
D:phosphatidylinositol
答案: triglyceride
7、 A lipid bilayer is the fundamental structural component of all cell membranes.
A:正确
B:错误
答案: 正确
8、 Maintenance of the lipid bilayer in the plasma membrane requires special enzymes and the hydrolysis of ATP.
A:正确
B:错误
答案: 错误
9、 The most abundant lipids in cell membranes are ____.
答案: phospholipids
10、 Sugar-containing lipids called ______ are found only in the outer half of the bilayer and their sugar groups are exposed ac the cell surface.
答案: glycolipids
Culturing and visualizing cells Culturing and visualizing cells-test
1、 The most direct source of monoclonal antibodies are __ cells.
A:B lymphocytes
B:T lymphocytes
C:myeloma
D:Hybridoma
答案: Hybridoma
2、 The fluorescent properties of dyes such as FITC can provide information on the
A:location of specific proteins.
B:concentration of ions in specific regions of the cell.
C:the amount of DNA in a cell.
D:volume of a cell.
答案: location of specific proteins.
3、 What factors necessary for growth of animal cells in culture are provided by serum?
A:amino acids
B:precursors of DNA synthesis
C:growth factors
D:vitamins
答案: growth factors
4、 What is the advantage of using GFP-tag to visualize specific proteins, instead of staining cells with fluorescent dyes that bind to the target protein?
A:GFP fusions enable one to track changes in the location of the protein in living cells; staining usually requires fixed cells
B:GFP fusions enable higher resolution than staining with fluorescent probes.
C:GFP permits the position of the protein in the cell more precisely than fluorescent probes
D:GFP fusions are not subject to artifacts; fluorescent probes may introduce background artifacts.
答案: GFP fusions enable one to track changes in the location of the protein in living cells; staining usually requires fixed cells
5、 Which one cleaves pre-miRNA in the cytoplasm to produce miRNA?
A:Dicer
B:RISC
C:shRNA
D:siRNA
答案: Dicer
6、 A single monoclonal antibody can bind to several different sites on an antigen
A:正确
B:错误
答案: 错误
7、 RNAi can be mediated just by introducing the already processed miRNA/siRNA into cells
A:正确
B:错误
答案: 正确
8、 _______ degrades mRNAs with sequences complementary to a bound siRNA
答案: RISC
Transmembrane transport of Ions and small molecules
1、 Classes of membrane transport proteins include all of the following except
A:ATP-powered pumps.
B:ion channels.
C:protein translocons.
D:transporters.
答案: protein translocons.
2、 The glucose uniporter GLUT1 has a Km of 1.5 mM for D-glucose and 30 mM for D-galactose. At a concentration of 5 mM for each, what is the rate of glucose transport relative to galactose transport? The Vmax may be assumed to be the same for both.
A:3.7-fold slower
B:equal
C:5.5-fold faster
D:20-fold faster
答案: 5.5-fold faster
3、 How does uniport transport compare to simple diffusion?
A:Similar to simple diffusion, uniport transport is nonspecific
B:Uniport transport is slower but more specific than simple diffusion
C:Uniport transport is much faster and more specific than simple diffusion.
D:Simple diffusion is reversible but uniport transport is not.
答案: Uniport transport is much faster and more specific than simple diffusion.
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